eBooks have always been a problem for blind screenreader users. Legal eBooks are kept heavily protected to stop you copying or sharing them, which means it’s hard for assistive technology to get into them and read them back. Governments have been lobbied to clamp down on file-sharing sites where you can get eBooks that read easily. And anything complex in layout, like a textbook, usually has shoddy text-to-speech support.
There are ways to do it, like using iBooks on iPad or getting books from Bookshare and other organisations. But that’s not every book, and that means an additional process that sighted users don’t have to follow.
Good news, then, that Amazon has updated its Kindle Apps. This lets you get text-to-speech to read out loads more books, and you can still change the content (colour, font size) to make it easier to read if you have some sight. This includes Amazon Kindle for Windows PC.
All taken from this great write-up at the CALL Scotland blog, which I recommend you go read: Giving your Kindle App a voice.